Dr. Loretta Intense Replenishing Serum in Beauty: NA. Dr. Loretta Intense Replenishing Serum in Beauty: NA. Your skin deserves the TLC of Dr. Loretta's Intense Replenishing Serum. This hydrating serum plumps skin's appearance while increasing luminosity and smoothness. Antioxidant Lipochroman, vitamin E, and linoleic acid protect against free radical damage caused by pollution and UV radiation - the leading causes of fine lines and dark spots.. Glycolipids replenish moisture loss caused by climate conditions, while vitamins E and F calm skin redness. Can be used on sensitive and post-procedure skin. Free of sulfates, parabens, phthalates, artificial dyes, and artificial fragrance. 1 fl oz. After cleansing, apply to face, neck and back of hands; can be used AM and PM. Can be mixed with any Dr Loretta serum in the palm of the hand and applied to treatment areas to boost skin hydration. Follow with Intense Brightening Cream. DLTA-WU4. 229. As a dermatologist with 40 years of experience, Dr. Loretta's passion is helping women feel confident at every age. She created the first skincare line that shields the skin against environmental factors responsible for 85% of skin aging - indoor and outdoor pollution, UVA, UVB and HEV, climate change and irritants. Dr. Loretta products combine high concentrations of medical grade actives and botanical ingredients to ensure healthier, more youthful skin.